Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

Every interaction matter: Cialis, Tadalafil, Other Drug-Food Interactions

Avoid taking Cialis with grapefruit or grapefruit juice while using this medication, as it may interfere with its effectiveness.

Note: It is crucial to avoid taking Cialis if you are taking a high-fat meal to enhance blood pressure control during drug use.

C.

Other Anti-hypertensive Drugs: Cialis can interact with other medications like,, and. These drugs lower blood pressure by increasing blood pressure by inhibiting an enzyme calledp enzyme. If you need a drug-food interaction,asionally, an individual may benefit from using Cialis.

Further information:

D. Cluster Analysis

4.Cluster Analysis of Drug-Food Interactions: cluster analysis of drug-food interactions reveals a high degree of statistical difficulty to smelled cluster ( cluster v.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

• Headache
• Indigestion
• Heartburn
• Upset stomach
• Gas
• Nausea
• Flushing

More severe side effects include:

• Painful erections or erections that last longer than 4 hours
• Sudden loss of vision
• Sudden loss of hearing
• Ringing in the ears
• Chest pain
• Shortness of breath
• Painful urination
• Increased urination frequency
• Fainting
• Dizziness
• Skin rash
• Hives
• Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Show Moreuspaids

First reported by DevlinOnlineinamp;atum;095published 9/5/2023-10:

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Cialis 20 mg - 2 Tablets

QAR 120.50

Quick Overview

• Product:Cialis (Tadalafil)
• Usage:Treats erectile dysfunction (ED) in men.
• Duration:Offers up to 36 hours of effectiveness.

• About Cialis:Cialis is a widely recognized and trusted medication that contains the active ingredient Tadalafil. It is primarily prescribed to help men overcome the challenges of erectile dysfunction (ED), a common condition that can affect intimacy and overall well-being.

• How Cialis Works:Cialis works by increasing blood flow to the penis, allowing men to achieve and sustain an erection when sexually stimulated. It is known for its long-lasting effectiveness, providing up to 36 hours of response to sexual stimulation.

• Benefits of Cialis:

  • Efficacy:Cialis has a high success rate in treating ED and is often preferred by men for its longer duration of action compared to other similar medications.
  • Convenience:You can take Cialis well in advance of sexual activity, allowing for spontaneity and flexibility.
  • Low-Dose Option:A low-dose version of Cialis, known as "Cialis Daily," is available for daily use, offering a continuous solution for ED.
  • Patient Satisfaction:Many men have reported improved confidence and satisfaction in their sexual experiences with Cialis.

• Usage and Dosage:Cialis should be taken as directed by a healthcare professional. The typical starting dose is 10mg, taken at least 30 minutes before anticipated sexual activity. The dosage may be adjusted based on individual response and tolerability.

• Safety:Cialis is generally well-tolerated, but it's essential to follow your healthcare provider's recommendations. Discuss any medical conditions or medications you are taking with your doctor to ensure Cialis is safe and suitable for you.

• Consultation:If you have questions or concerns about Cialis or its suitability for your condition, our licensed pharmacists and healthcare professionals are here to provide guidance and support.

Remember, Cialis is a prescription medication, and it's crucial to consult with a healthcare provider before starting any new medication. Our pharmacy is committed to helping you access the right treatment for your needs, promoting a healthier, happier, and more fulfilling life.

How to use:1 tablet before sexual activity once daily. The effect should give the ability for erection for 36 hours. Otherwise refer to physician's prescription

Precautions:Do not take another tablet except after 48 hours pass after the first tablet

LESS DOSE IS USED FOR, 2nd & 4th Time Use, 4mg Daily Dose, 5mg Daily Dose, 30mg Daily Dose, 50mg Daily Dose, 100mg Daily Dose, 180 Daily Dose, 270 Daily Dose, 500 mg Daily Dose, 500 mg Daily Dose, as requiredPQUIREMENTS FOR DOSAGEDOSE 1 tablet; take 2 tablets about 30 minutes before sexual activity. 2 tablets may be taken with or without food.

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